37e symposium du GRSNC
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Program

All lectures will be in English.

Please note that general practitioners (family physicians) and specialists can obtain continuing professional development credits for this activity. For more details, please consult the Accreditation section.

>>> Final program and abstracts booklet in Acrobat file format

Monday, May 4, 2015
A.M. 8h15 - 8h30 Welcome address
Trevor Drew, GRSNC Director
Geneviève Tanguay, Vice-Rector of Research, Creation and Innovation
Daniel Bourbonnais , Vice-Dean, Research and Scientific Innovation,
  Faculty of Medicine

Introduction
Jean-Claude Lacaille, Symposium Organizer
  8h30 - 9h15 Plenary Lecture
Samuel Berkovic
Epilepsy Research Centre,
University of Melbourne, Melbourne, AUSTRALIA

Genetics of Epilepsy at the clinic: Past, present and future.

SESSION 1
CLINICAL ASPECTS
Chairperson: Patrick Cossette, Université de Montréal
A.M. 9h15 - 9h45 Patrick Cossette
Département de neurosciences,
Université de Montréal, Montréal, QC, CANADA

Monogenic epilepsies.
  9h45 - 10h15 Heather C. Mefford
Division of Genetic Medicine,
University of Washington, Seattle, WA, U.S.A.

Genetic investigations of epileptic encephalopathy.
  10h15 - 10h35 Break
  10h35 - 11h05 William B. Dobyns
Department of pediatrics,
University of Washington, Seattle, WA, U.S.A.

Growth matters: somatic and germline mutations of core PI3K-AKT pathway genes cause a wide spectrum of developmental disorders including epilepsy.
  11h05 - 11h35 Jean Gotman
Montreal Neurological Institute & Hospital, Department of Neurology and Neurosurgery,
McGill University, Montréal, QC, CANADA

High Frequency Oscillations: a marker of epileptogenicity.
  11h35 - 12h05 Dang K. Nguyen
Département de neurosciences,
Université de Montréal, Montréal, QC, CANADA

Multimodal investigation of epileptic patients.
  12h05 - 13h00 Lunch
  13h00 - 14h00 Poster session


SESSION 2
MOLECULAR MECHANISMS
Chairperson: Jean-Claude Lacaille, Université de Montréal
P.M. 14h00 - 14h30 John Huguenard
Department of Neurology and Neurological Sciences,
Standford University School of Medicine, Standford, CA, U.S.A.

Mechanisms of thalamocortical seizures, from molecules to circuits.
  14h30 - 15h00 Stéphanie Baulac
Hôpital de la Pitié-Salpêtrière,
Institut du Cerveau et de la Moelle épinière (ICM), Paris, FRANCE

Molecular mechanisms of focal epilepsy.
  15h00 - 15h20 Break
  15h20 - 15h50 Edward C. Cooper
Department of Neurology, Neurosensory Center,
Baylor College of Medicine, Houston, TX, U.S.A.

Molecular mechanisms of KCNQ channel related epilepsy.
  15h50 - 16h20 Oscar Marín
MRC Centre for Developmental Neurobiology,
King’s College London, London, U.K.

Molecular mechanisms of interneuron diversity and cortical plasticity.
  16h20 - 17h30 Poster session
  18h00 Cocktail and Banquet
Agora Morris et Rosalind Goodman
Pavillon Jean-Coutu
Campus de l'Université de Montréal
2940, chemin de Polytechnique


Tuesday, May 5, 2015
SESSION 3
NEURONAL NETWORKS
Chairperson: Massimo Avoli, McGill University
A.M. 8h45 - 9h15 Ivan Soltesz
Department of Anatomy & Neurobiology,
School of Medicine, University of California, Irvine, CA, U.S.A.

Organization and control of epileptic circuits in temporal lobe epilepsy.
  9h15 - 9h45 Douglas A. Coulter
Abramson Research Center, University of Pennsylvania,
School of Medicine and Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A.

Seizure propagation in epileptic circuit.
  9h45 - 10h15 Christophe Bernard
INS-Institut de Neurosciences des Systèmes,
Aix-Marseille Université, Marseille, FRANCE

Mecanisms of seizure genesis and propagation.
  10h15 - 10h30 Break
  10h30 - 11h00 Rosa Cossart
Institut de neurobiologie de la méditerranée (INMED),
Aix-Marseille Université, Marseille, FRANCE

How inhibition shapes interictal spike dynamics in the awake epileptic mouse.
  11h00 - 11h30 Elsa Rossignol
CHU – Sainte-Justine, Département de neurosciences,
Université de Montréal, Montréal, QC, CANADA

Cortical GABAergic interneuron disorders and epileptic encephalopathies.
  11h30 - 12h30 Lunch
  12h30 - 13h30 Poster session


SESSION 4
ANIMAL MODELS AND THERAPIES
Chairperson: Lionel Carmant, Université de Montréal
P.M. 13h30 - 14h00 Wayne N. Frankel
The Jackson Laboratory, Bar Harbor, Maine, U.S.A.
Animal models of genetic epilepsy.
  14h00 - 14h30 Dimitri M. Kullmann
Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology,
University College London, London, U.K.

Gene therapy for epilepsy: how far from clinical translation?
  14h30 - 15h00 Gregory L. Holmes
Department of Neurological Sciences,
University of Vermont College of Medicine, Burlington, U.S.A.

Antiepileptic treatment strategies in neonatal epilepsy.
  15h00 - 15h15 Break
  15h15 - 15h45 Scott C. Baraban
Department of Neurological Surgery,
University of California, San Francisco, CA, U.S.A.

Personalized medicine-based drug discovery in zebrafish.
  15h45 - 16h15 H. Steve White
Anticonvulsant Drug Development Program, Department of Pharmacology and Toxicology,
University of Utah, Salt Lake City, UT, U.S.A.

From animals to humans: the importance of animal models in the early discovery of new therapies for epilepsy.
  16h15 - 16h45 Closing Address
David A. Prince
Neurology Department,
Stanford University School of Medicine, Stanford, CA, U.S.A.

Antiepileptogenic manipulations of excitatory and inhibitory synaptic connectivity after neocortical trauma.

 


We gratefully acknowledge the financial support of the following organizations:

Sponsors Baylis Medical Centre de recherche du CHUM Eisai Canada Faculté de médecine, Vice-décanat à la recherche et à l'innovation scientifique - Université de Montréal Centre de recherche du CHU Sainte-Justine FRQS UBC Canada Novartis Leica Microsystems Provincial Medical Université de Montréal - Vice rectorat à la recherche, création et innovation Fondation Savoy Sunovion
   

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